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Significant diminution of infarct size after an intravenous injection of recombinant HGF 5 min before reperfusion in a murine ischemia-reperfusion model. Ischemia was initiated for 60 min, followed by a 24 h reperfusion. Infarct size was measured by the enzymatic technique (TTC, Unisperse blue dye). n = 12 in the control group; n = 11 in the HGF group.

Journal: Frontiers in Cardiovascular Medicine

Article Title: Role of heparin-induced HGF release in the acute phase of STEMI

doi: 10.3389/fcvm.2025.1668882

Figure Lengend Snippet: Significant diminution of infarct size after an intravenous injection of recombinant HGF 5 min before reperfusion in a murine ischemia-reperfusion model. Ischemia was initiated for 60 min, followed by a 24 h reperfusion. Infarct size was measured by the enzymatic technique (TTC, Unisperse blue dye). n = 12 in the control group; n = 11 in the HGF group.

Article Snippet: Treatments were administered intravenously at 5 min before reperfusion [physiological saline (0.9% NaCl) or recombinant Mouse HGF Protein (2207-HG-025/CF, R&D Systems) at 0.3 mg/kg was injected via the tail vein].

Techniques: Injection, Recombinant, Control